Moreover, the use of honey in beverages is also increasingly popular. Honey was utilized as a natural sweetener from ancient period since it has high level of fructose (honey is 25% sweeter than tablet sugar). The water activity (WA) of honey is between 0.56 and 0.62 and its value of pH is almost 3.9. Honey no needs to refrigerate, it never spoils, and it can also be stored unopened at room temperature in a dry place. Honey is reviewed as a balanced diet and equally popular for male and female in all ages. Honey is the only insect-derived natural product, and it has nutritional, cosmetic, therapeutic, and industrial values. Most ancient population, including the Greeks, Chinese, Egyptians, Romans, Mayans, and Babylonians, consumed honey both for nutritional aims and for its medicinal properties. Honey has been used by humans since ancient times, nearly 5500 years ago. Honey is a natural product formed from nectar of flowers by honeybees ( Apis mellifera Family: Apidae). Based on these facts, the use of honey in clinical wards is highly recommended. Sufficient evidence exists recommending the use of honey in the management of disease conditions. In conclusion, honey could be considered as a natural therapeutic agent for various medicinal purposes. According to modern scientific literature, honey may be useful and has protective effects for the treatment of various disease conditions such as diabetes mellitus, respiratory, gastrointestinal, cardiovascular, and nervous systems, even it is useful in cancer treatment because many types of antioxidant are present in honey. Flavonoids and polyphenols, which act as antioxidants, are two main bioactive molecules present in honey. Honey has a potential therapeutic role in the treatment of disease by phytochemical, anti-inflammatory, antimicrobial, and antioxidant properties. Many evidences suggest the use of honey in the control and treatment of wounds, diabetes mellitus, cancer, asthma, and also cardiovascular, neurological, and gastrointestinal diseases. The ingredients of honey have been reported to exert antioxidant, antimicrobial, anti-inflammatory, antiproliferative, anticancer, and antimetastatic effects. Traditionally, honey is used in the treatment of eye diseases, bronchial asthma, throat infections, tuberculosis, thirst, hiccups, fatigue, dizziness, hepatitis, constipation, worm infestation, piles, eczema, healing of ulcers, and wounds and used as a nutritious supplement. The aim of this review is to emphasize the ability of honey and its multitude in medicinal aspects.
Honey is used not only as a nutritional product but also in health described in traditional medicine and as an alternative treatment for clinical conditions ranging from wound healing to cancer treatment. Honey is one of the most appreciated and valued natural products introduced to humankind since ancient times.
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